[Epub ahead of print] Vo NX, Le NNH, Chu TDP, et al
At the heart of this complex web is glutathione, the bodys most potent natural antioxidant and detoxifier
This is consistent with the fact that examination of the fatty-acid oxidation pathway in fibroblast culture did not reveal any abnormalities to explain the elevations in acyl-carnitines
As for the culture environment in vitro, where only AML cells are present, orid-liposome-MAL can non-competitively enter all AML cells, causing REDOX imbalance and exerting its anti-tumor effects
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The intron-tagged mScarlet-Metallothionein 1E ( mScarlet-MT1E ) 1321N1 cell line was generated as described previously (Reicher et al, 2020)